Zebrafish and Medaka

Zebrafish and Medaka Embryos at RARAF

An exciting development at RARAF is the ability to irradiate Zebrafish and Medaka embryos at several different stages of development.


Studies on cardiac morphogenesis using the zebrafish embryo model at the Columbia microbeam. The left image shows a 4X view taken at RARAF of the outline of a 52 h post fertilization zebrafish embryo whose heart is highlighted in the yellow rectangle. As shown on the right (40X view), the cells of the atrium and the ventricle are green fluorescent protein (GFP)- or red fluorescent protein (RFP)-tagged, respectively. In the context of cardiac regeneration studies, the function of a specific region of the heart (e.g. atrium) can be determined upon microbeam irradiation of another region of the heart (e.g. ventricle).